Plague - World Health Organization (WHO)
2022年7月7日 · Confirmation of plague requires lab testing. The best practice is to identify Y. pestis from a sample of pus from a bubo, blood or sputum. A specific Y. pestis antigen can be detected by different techniques. One of them is a laboratory validated rapid dipstick test now widely used in Africa and South America, with the support of WHO. Treatment
Plague - World Health Organization (WHO)
2024年9月25日 · Plague is an infectious disease caused by Yersinia pestis bacteria, usually found in small mammals and their fleas. The disease is transmitted between animals via their fleas and, as it is a zoonotic bacterium, it can also transmit from animals to humans.
Manual for plague surveillance, diagnosis, prevention and control
2024年9月25日 · Key revisions include the use of rapid diagnostic tests in varied contexts, the inclusion of fluoroquinolones as a first-line treatment option, and updated protocols for personal protective equipment when handling plague-infected corpses. These recommendations were published in 2021 and are based on evidence reviewed during an international expert meeting …
Plague - Madagascar - World Health Organization (WHO)
2021年10月1日 · Preliminary results showed a carriage of Yersinia pestis, the causative bacterium, in 1.3% of the rats, exceeding the alert threshold of 1%, while the pulicidal index (the ratio between the total number of fleas collected from rats captured over the total number of rats captured) was 1.7, which did not exceed the alert threshold of more than 5 ...
Plague Outbreak Toolbox - World Health Organization (WHO)
Isolation of Y. pestis from a clinical sample - must have appropriate colony morphology and be identified as Y. pestis based by at least two of the following: phage lysis at 20-25ºC; biochemical profile; F1 antigen detection; Seroconversion or a 4-fold difference in anti-F1 antibody titer in paired serum samples drawn at least 2 weeks apart
• an isolate from a clinical sample identified as Y. pestis (colonial morphology) and two of the four following tests must be positive: o Phage lysis of cultures at 20–25 °C and 37 °C; o F1 antigen detection; o PCR detection of Y. pestis; o Y. pestis biochemical profile; or
WHO guidelines for plague management: revised …
2021年5月27日 · Plague is an acute bacterial infection caused by Yersinia pestis. Although effective antimicrobials are available, plague still has high mortality because most outbreaks take place in remote places, where proper diagnosis and treatment remain challenging. Early identification of the disease is crucial to ensure prompt treatment and better outcomes.
Peste - World Health Organization (WHO)
2022年7月7日 · Le bacille, Y. pestis, pénètre dans l’organisme lors de la piqûre, passe dans le système lymphatique et atteint le ganglion le plus proche où il se réplique. Il en résulte une inflammation du ganglion avec tension douloureuse des tissus: c’est ce qu’on appelle le «bubon».
Plague – Madagascar - World Health Organization (WHO)
2017年11月27日 · The Institut Pasteur Madagascar has cultured 33 isolates of Yersinia pestis, which were all sensitive to the antibiotics recommended by the National Program for the Control of Plague. Plague is endemic in some areas of Madagascar and additional cases of plague may occur, at least until the end of the plague season in April 2018.
Plague - World Health Organization (WHO)
2017年10月23日 · Plague bacillus, Y. pestis, enters at the bite and travels through the lymphatic system to the nearest lymph node where it replicates itself. The lymph node then becomes inflamed, tense and painful, and is called a "bubo". At advanced stages of infection the inflamed lymph nodes can turn into open sores filled with puss.