Rewarming: facts and myths from the systemic perspective
2012年6月7日 · Rewarming is a delicate phase of therapeutic hypothermia (TH). Adverse consequences of rewarming on the whole body may seriously limit the protective effects of hypothermia, leading to secondary injury. Thus, understanding, predicting, and managing possible systemic side effects of rewarming is important for guaranteeing TH efficacy.
Rewarming: facts and myths from the neurological perspectives
2012年6月7日 · Standard operating procedures both for scientific study protocols as well as in routine daily practice stress the importance of slow rewarming after targeted temperature management/moderate therapeutic hypothermia (32 to 34°C) [1–3]. The recommended rewarming speed ranges from 0.1 to 0.4°C/hour, the former allowing a minimum of 24 hours to ...
The physiologic responses to epinephrine during cooling and after ...
2011年9月23日 · Introduction The purpose of our study was to determine whether hypothermia has any effects on physiological hemodynamic responses to epinephrine (Epi), and whether rewarming reverses these effects. Methods Sprague-Dawley rats were instrumented to measure mean arterial pressure (MAP), and left ventricular (LV) pressure-volume changes were recorded by using a Millar pressure-volume conductance ...
A recommended early goal-directed management guideline for …
2016年4月20日 · Passive rewarming allows the patient’s intrinsic heat-generating mechanisms to counteract heat loss. The natural rewarming rate is 1.20 °C/h while shivering can increase the rate up to 3.6 °C/h . Passive mechanisms include removal of wet clothing, augmenting the environmental temperature, and applying a warm blanket.
Pharmacodynamics in hypothermia | Critical Care | Full Text
2012年6月7日 · Rewarming shock is a clinically descriptive term that refers to a pathophysiologic state of cardiovascular collapse taking place during or after rewarming from accidental hypothermia , recognized as a progressive reduction of CO and a sudden fall in arterial blood pressure. In order to treat or prevent rewarming shock, cardioactive inotropic ...
Neonatal Hypothermia - Page 18 - Medscape
Rewarming: Slowly Achieving a Normothermic Temperature Although the risk for seizures increases with rewarming, a discussion is warranted to review other risk factors associated with this process. ...
High-flow nasal cannula for body rewarming in hypothermia
2020年3月30日 · Over a 6-month period (October 2018–March 2019), we applied, for clinical purposes, HFNC with no oxygen supplementation to 4 patients (3 females, median [interquartile range] age 51 [67–86] years), who were admitted to the emergency department of our institution with stage 1–2 primary hypothermia (i.e., prolonged exposure to cold environment) [].
Neonatal Hypothermia - Page 11 - Medscape
Hypotension may also occur secondary to hypovolemia, reduced cardiac output, and reduced stroke volume. A reduced blood flow and hyperviscosity have been reported in the hypothermic infant, which ...
Hyperoxia for accidental hypothermia and increased mortality: a …
2023年4月1日 · Background Supraphysiologic oxygen administration causes unfavorable clinical outcomes in various diseases, including traumatic brain injury, post–cardiac arrest syndrome, and acute lung injury. Accidental hypothermia is a critical illness that reduces oxygen demands, and excessive oxygen is likely to emerge. This study aimed to determine whether hyperoxia would be associated with increased ...
High Quality Targeted Temperature Management (TTM) After …
2020年1月6日 · Targeted temperature management (TTM) is a complex intervention used with the aim of minimizing post-anoxic injury and improving neurological outcome after cardiac arrest. There is large variability in the devices used to achieve cooling and in protocols (e.g., for induction, target temperature, maintenance, rewarming, sedation, management of post-TTM fever). This variability can explain the ...