Drug Efficacy in the Treatment of Antipsychotic-Induced Akathisia
2024年3月7日 · Meaning Vitamin B 6 may have the most favorable efficacy and tolerability profile, followed by mirtazapine and biperiden, for the treatment of antipsychotic-induced akathisia. Abstract
The Assessment and Treatment of Antipsychotic-Induced Akathisia
The evidence to support the use of the anticholinergic medications benztropine and biperiden for the treatment of antipsychotic-induced akathisia is extremely limited and at high risk of bias, with inconsistent findings among trials regarding efficacy.
Drug Efficacy in the Treatment of Antipsychotic-Induced Akathisia
Vitamin B 6 may have the most favorable efficacy and tolerability profile, followed by mirtazapine and biperiden, for the treatment of antipsychotic-induced akathisia. This systematic review with network meta-analysis compares the efficacy associated with 10 drugs for the treatment of antipsychotic-induced akathisia.
Revisiting Antipsychotic-induced Akathisia: Current Issues ...
In patient with antipsychotic-induced akathisia with parkinsonism, anticholinergic agents (e.g. biperiden, trihexyphenidyl, benztropine) are reasonable therapeutic options. The anxiolytic and sedative effects of benzodiazepines alone or in combination with propranolol may be beneficial for treating akathisia in selected patients.
Intravenous biperiden in akathisia: an open pilot study
Following the development of akathisia, 5 mg of biperiden was intravenously injected in seventeen patients and intramuscularly in six patients. The therapeutic effect of biperiden on akathisia was clinically assessed by using the rating scale of Barnes.
Intravenous Biperiden in Akathisia: An Open Pilot Study
It has been shown that intramuscular biperiden is a relatively rapid and effective treatment for akathisia. However, the intravenous administration of biperiden may provide a more rapid effect, although this remains to be definitively proven.
The effectiveness of intramuscular biperiden in acute ...
Our results suggest that intramuscular biperiden should not be considered as a first-line treatment of NIA. Neuroleptic-induced acute akathisia (NIA) is a distressing condition and an important clinical problem because it is associated with treatment noncompliance and suicidal or …
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