Brain RNA-Seq – Brain RNA-Seq
Mouse data - Zhang et al. (2014) An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J Neurosci 34(36):11929-11947. PMID: 25186741.
Cell Types Database: RNA-Seq Data - brain-map.org - Allen Brain …
Single cell (or single nucleus) RNA sequencing (RNA-Seq) is a scalable approach to provide genome-wide expression profiles for thousands of cells. This data set includes single cell and nuclear transcriptomic profiles, assayed from human and mouse brain regions.
A high-resolution transcriptomic and spatial atlas of cell types in …
2023年12月13日 · Single-cell transcriptomics by single-cell RNA sequencing (scRNA-seq) or single-nucleus RNA sequencing (snRNA-seq) provides unprecedented profiling depth and scalability, enabling comprehensive...
Single-cell and spatial transcriptomics: deciphering brain ... - Nature
2023年5月17日 · Single-cell RNA sequencing technologies increase our understanding of pathomechanisms of brain disorders, providing information on selective neuronal vulnerability, neuroimmune...
Brain Cell Type Specific Gene Expression and Co-expression …
2018年6月11日 · To interrogate the interactions of genes within each of the human brain cell types, we applied MEGENA, a multiscale clustering algorithm, to RNA-seq data from the human Darmanis et al. data set ...
Transcriptomic diversity of cell types across the adult human brain …
2023年10月13日 · In this work, we used single-nucleus RNA sequencing to systematically survey cells across the entire adult human brain. We sampled more than three million nuclei from approximately 100 dissections across the forebrain, midbrain, and …
Brain RNA-Seq - Database Commons - National Genomics Data …
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. [PMID: 25186741]
Single cell sequencing of brain cell transcriptomes and epigenomes
2021年1月1日 · In this Primer, we describe how high-throughput single-cell sequencing assays enable high-resolution, broad-scope analysis of brain cell types. Sequencing DNA and/or RNA quantifies the information-bearing molecules that encode and enact each cell’s biological identity.
Single-Cell Sequencing of Brain Cell Transcriptomes and …
2021年1月6日 · Single-cell sequencing technologies measure RNA or DNA from individual cells without the need for selective cell purification. These techniques can be summarized by three characteristics: scope (number of cells), granularity (number of genes or epigenetic features), and spatial resolution (Figure 1 B).
Cell types in the mouse cortex and hippocampus revealed by ... - Science
2015年2月19日 · Normal brain function relies on a diverse set of differentiated cell types, including neurons, glia, and vasculature. Here, we have used large-scale single-cell RNA sequencing (RNA-seq) to classify cells in the mouse somatosensory cortex and hippocampal CA1 region.
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