Gossypol - Wikipedia
Gossypol (/ ˈ ɡ ɒ s ə p ɒ l /) is a natural phenol derived from the cotton plant (genus Gossypium). Gossypol is a phenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes. It is a yellow pigment. The structure exhibits atropisomerism, with the two enantiomers having different biochemical properties. [1]
棉酚 - 百度百科
棉酚（gossypol）是一种黄色多酚羟基双萘醛类化合物，主要存在于锦葵植物棉花的根、茎、叶和种子内，棉籽仁中含量最高。 棉酚是锦葵科植物草棉、树棉或陆地棉成熟种子、根皮中提取的一种多元酚类物质，具有抑制精子发生和精子活动的作用。
GOSSYPOL - Uses, Side Effects, and More - WebMD
Gossypol is a pigment that is found in certain plants, including the cotton plant. It is found in the seeds, stem, and roots. It's used as medicine. Gossypol interferes with sperm development...
棉酚 - 维基百科，自由的百科全书
棉酚 （英語： Gossypol）是一种存在于 棉花 的 棉籽 及棉根皮中的 多酚 类物质。 黄色晶体，有三种晶形。 有毒，难溶于水，微溶于 石油醚，溶于稀 碳酸钠 溶液、 氨水 （同时缓慢分解）、 甲醇 、 乙醇 、 乙醚 、 氯仿 、 二甲基甲酰胺。 可从 棉籽油 中提取或通过化学方法合成得到。 用作 聚乙烯 稳定剂、橡胶抗氧剂、 杀虫剂 等。 科学家在研究食用粗制棉籽油造成 不育 时，发现棉酚具有男用抗生育活性。 后进行了大量动物试验和上万名受试者的临床观察后证实，棉酚有良 …
Gossypol (BL 193，棉酚) - 仅供科研 | Bcl-2 Family拮抗剂 | MCE
Gossypol，一种从棉籽和根中分离出来的天然产物，已被研究用作抗癌剂。 Gossypol 的外消旋形式已在多项临床试验中进行测试，耐受性良好。 外消旋形式Gossypol 与 Bcl-xL 蛋白结合，K i 为 0.5 至 0.6 μM。
Gossypol Uses, Benefits & Dosage - Drugs.com Herbal Database
2024年8月16日 · Gossypol is a nonsteroidal compound that inhibits sperm production and motility in a variety of male animals and in humans, but it does not affect sex hormone levels or libido. Gossypol exerts its contraceptive action by inhibiting enzyme systems that play a crucial role in energy metabolism in sperm and spermatogenic cells.Coutinho 2002, Wang 2009
Gossypol and Its Natural Derivatives: Multitargeted …
Several gossypol derivatives, including apogossypol, ApoG2, gossypolone, and gossypol Schiff base, have been isolated and evaluated for their anticancer effects. In this review, we provide a systematic analysis of the antineoplastic activity of gossypol and its derivatives, summarize the in vitro, in vivo, and clinical trials, and discuss ...
Gossypol | C30H30O8 | CID 3503 - PubChem
2009年7月9日 · Gossypol, a natural compound present in cottonseeds, displays antiproliferative and pro-apoptotic effects against various cancer cells. The (-)-gossypol enantiomer is a more potent inhibitor of cancer cell growth. Here, the molecular mechanisms of apoptosis induced by (-)-gossypol were studied in human prostate cancer cells.
Gossypol - an overview | ScienceDirect Topics
Gossypol (C30 H 30 O 8), which is found throughout the cotton plant, is a naturally occurring toxin that deters insect pests. It is a yellow, polyphenolic aldehyde compound, which is present in the highest concentrations in CS pigment glands (Blauwiekel et al., 1997). Gossypol exists in CS in both free and bound forms.
Gossypol and Its Natural Derivatives: Multitargeted ... - MDPI
2022年11月28日 · Gossypol, a natural polyphenolic compound derived from the seeds, roots, and stems of cotton (Gossypium hirsutum L.), was first used as a male contraceptive agent.