Glutamine synthetase - Wikipedia
Glutamine synthetase (GS) (EC 6.3.1.2) [3] is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form …
Glutamine: Metabolism and Immune Function, Supplementation …
Glutamine synthesis by the GS depends on glutamate availability. Glutamate, in turn, is synthesized from 2-oxoglutarate NH 4, through the action of the glutamate dehydrogenase, or …
Glutamine Synthetase - Chemistry LibreTexts
Glutamine synthetase (GS) is an enzyme that is responsible for catalyzing the reaction that synthesizes glutamine from glutamate and ammonia. Additionally, GS catalyzes the reverse …
Glutamine - Wikipedia
Glutamine synthesis from glutamate and ammonia is catalyzed by the enzyme glutamine synthetase. The majority of glutamine production occurs in muscle tissue, accounting for about …
Glutamine Synthetase: Localization Dictates Outcome - PMC
Glutamine synthetase (GS) is the adenosine triphosphate (ATP)-dependent enzyme that catalyses the synthesis of glutamine by condensing ammonium to glutamate. In the circulatory …
A glutamine metabolic switch supports erythropoiesis | Science
We discovered pervasive metabolic changes, including a prominent metabolic switch from glutamine catabolism to synthesis during erythroid maturation. Glutamine synthetase (GS), …
Structural Analysis of Glutamine Synthetase from - Nature
2018年8月3日 · Glutamine synthetase (GS) is an enzyme that regulates nitrogen metabolism and synthesizes glutamine via glutamate, ATP, and ammonia. GS is a homo-oligomeric protein of …
Glutamine Synthetase - an overview | ScienceDirect Topics
Glutamine synthetase is a cytosolic enzyme that catalyzes the synthesis of glutamine from glutamate and free NH 4 + in an ATP-dependent reaction (Fig. 1). The human gene encoding …
Structure–function relationships of glutamine synthetases
2000年3月7日 · As a highly regulated enzyme at the core of nitrogen metabolism, glutamine synthetase has been studied intensively. We review structural and functional studies of both …
Differences in regulation mechanisms of glutamine synthetases …
2024年1月19日 · Glutamine synthetases (GS) catalyze the ATP-dependent ammonium assimilation, the initial step of nitrogen acquisition that must be under tight control to fit cellular …