Histone H2A.Z - Wikipedia
Histone H2AZ is a variant of histone H2A, and is used to mediate the thermosensory response, and is essential to perceive the ambient temperature. Nucleosome occupancy of H2A.Z decreases with temperature, and in vitro assays show that H2A.Z-containing nucleosomes wrap DNA more tightly than canonical H2A nucleosomes in Arabidopsis.
The histone variant H2A.Z in gene regulation - PMC - PubMed …
The histone variant H2A.Z is involved in several processes such as transcriptional control, DNA repair, regulation of centromeric heterochromatin and, not surprisingly, is implicated in diseases such as cancer. Here, we review the recent developments on H2A.Z focusing on its role in transcriptional activation and repression.
The histone variant H2A.Z in gene regulation - PubMed
2019年6月14日 · The histone variant H2A.Z is involved in several processes such as transcriptional control, DNA repair, regulation of centromeric heterochromatin and, not surprisingly, is implicated in diseases such as cancer. Here, we review the recent developments on H2A.Z focusing on its role in transcriptional …
The histone variant H2A.Z in gene regulation - Epigenetics
2019年6月14日 · The histone variant H2A.Z is involved in several processes such as transcriptional control, DNA repair, regulation of centromeric heterochromatin and, not surprisingly, is implicated in diseases such as cancer. Here, we review the recent developments on H2A.Z focusing on its role in transcriptional activation and repression.
Histone variant H2A.Z modulates nucleosome dynamics to …
2023年2月11日 · Nucleosomes, containing histone variants H2A.Z, are important for gene transcription initiation and termination, chromosome segregation and DNA double-strand break repair, among other functions.
Role of the histone variant H2A.Z.1 in memory, transcription, and ...
2024年2月16日 · Histone H2A.Z is a highly conserved H2A variant that suppresses memory in male mice [2, 8, 9, 11, 12, 13]. H2A.Z is encoded by 2 genes that produce histones H2A.Z.1 (encoded by H2afz) and...
Hierarchical Accumulation of Histone Variant H2A.Z Regulates
Early embryos undergo extensive epigenetic reprogramming to achieve gamete-to-embryo transition, which involves the loading and removal of histone variant H2A.Z on chromatin. However, how does H2A.Z regulate gene expression and histone modifications during preimplantation development remains unrevea …
Genome-wide identification of histone H2A and histone variant H2A.Z …
2017年9月1日 · H2A is a nucleosome core subunit involved in organizing DNA into a chromatin structure that is often inaccessible to regulatory enzymes. Replacement of H2A by its variant H2A.Z renders...
What makes a histone variant a variant: Changing H2A to become H2A.Z …
2021年12月6日 · H2A.Z, a variant of the H2A core histone family, plays a distinct and essential role in a diverse set of biological functions including gene regulation and maintenance of heterochromatin-euchromatin boundaries.
Deposition of histone variant H2A.Z within gene bodies …
H2A.Z, one of the most conserved but enigmatic histone variants that is enriched at the transcriptional start sites of genes, has been implicated in a variety of chromosomal processes. Recently, we reported a genome-wide anticorrelation between H2A.Z and DNA methylation, an epigenetic hallmark of heterochromatin that has also been found in the ...