Perioperative management of myasthenia gravis - PMC
Describe the pathophysiology, clinical features and management of myasthenia gravis. Discuss the key considerations and challenges in the perioperative management of these patients presenting for surgery or obstetric care.
Anesthesia and Surgery in Myasthenia Gravis Patients. By Kourosh Rezania, M.D., Associate Professor Department of Neurology, University of Chicago. Myasthenia gravis (MG) is an autoimmune disease caused by abnormal immune reaction directed against acetylcholine receptors or other proteins of the neuromuscular junction. As the result of ...
Myasthenia gravis - Diagnosis and treatment - Mayo Clinic
Jun 22, 2023 · Surgery. Some people with myasthenia gravis have a tumor in the thymus gland. If you have a tumor, called a thymoma, you'll need surgery to remove the thymus gland, called thymectomy. Even if you don't have a tumor in the thymus gland, removing the gland might improve your symptoms. However, the benefits of this surgery can take years to develop.
Myasthenia gravis surgery: Purpose, benefits, risks, and more
Jul 26, 2024 · Myasthenia gravis (MG) surgery involves removing the thymus in a procedure called a thymectomy. A surgeon can remove the thymus using a robot- or video-assisted minimally invasive procedure.
Myasthenia Gravis | Columbia Surgery
Myasthenia Gravis is a chronic autoimmune condition; Treatment involves surgical removal of the thymus, which can be done in a number of ways; Non-surgical options such as plasmapheresis, immunoglobulin, and medications can help treat symptoms of myasthenia gravis but …
Surgery for Myasthenia Gravis: Understanding the Benefits and …
Feb 9, 2024 · Surgery for Myasthenia Gravis: Who Is It For? Early surgery for myasthenia gravis may be the best option for: Individuals with a recent diagnosis; People with an enlarged thymus; Young adults (typically below 50) Note that the use of thymectomy for MG is an area of research, and more controlled trials are needed to confirm the findings.
Myasthenia Gravis Surgical Management - Rare Disease Advisor
Myasthenia gravis (MG) is a rare autoimmune disease characterized by the production of antibodies to various proteins in the neuromuscular junction (NMJ). 1,2 Several antigens trigger antibody production, specifically nicotinic acetylcholine receptor (n-AChR), muscle-specific kinase (MuSK), and lipoprotein-related protein 4 (LPR4). 3 Patients ...
Anesthesia and Surgery for Myasthenia Gravis: What You Need …
Jun 10, 2024 · When living with myasthenia gravis (MG), you may need to be more careful with medical procedures. Surgery often requires local or general anesthesia and sedating medications that prevent you from feeling pain. These medications work by relaxing the skeletal muscles during the procedure.
Myasthenia Gravis - OpenAnesthesia
Mar 8, 2024 · When possible, elective surgeries should be performed when MG patients are in remission. Ideally, surgical procedures should be scheduled in the morning when these patients have peak muscle function. Premedication with opioids, benzodiazepines, and barbiturates should be avoided due to depressed respiratory function in many MG patients.
Thymectomy in Myasthenia Gravis: A Narrative Review - PMC
Thymectomy has increasingly been used as a treatment modality for MG. Several observational studies have shown that thymectomy results in improvement in MG and a randomized trial has established that thymectomy leads to a better outcome in non-thymomatous generalized MG.