PDIP46 (DNA polymerase δ interacting protein 46) is an activating ...
2016年2月2日 · PDIP46 (SKAR, POLDIP3) was discovered through its interaction with the p50 subunit of human DNA polymerase δ (Pol δ). Its functions in DNA replication are unknown. PDIP46 associates with Pol δ in cell extracts both by immunochemical and protein separation methods, as well as by ChIP analyses.
Regulation and Modulation of Human DNA Polymerase δ Activity …
PDIP46 is a novel activator of Pol δ4, and the impact of this function is discussed in relation to its potential roles in DNA replication. Several new models for the roles of Pol δ3 and Pol δ4 in leading and lagging strand DNA synthesis that integrate a role for PDIP46 are presented.
Regulation and Modulation of Human DNA Polymerase δ …
2017年7月24日 · PDIP46 is a novel activator of Pol δ4, and the impact of this function is discussed in relation to its potential roles in DNA replication. Several new models for the roles of Pol δ3 and Pol δ4 in leading and lagging strand DNA synthesis that …
PDIP46 (DNA polymerase δ interacting protein 46) is an activating ...
2016年1月27日 · PDIP46 associates with Pol δ in cell extracts both by immunochemical and protein separation methods, as well as by ChIP analyses. PDIP46 also interacts with PCNA via multiple copies of a novel...
Human enhancer of rudimentary is a molecular partner of PDIP46…
2006年9月19日 · PDIP46/SKAR is so far the only identified substrate of S6K1 that has been shown to influence cell size. Our finding that ER is a molecular partner of PDIP46/SKAR and that interaction has an opportunity to occur universally in the mammalian cells raises a question about the role for ER in the cell growth control.
PDIP46 (DNA polymerase δ interacting protein 46) is an activating ...
2016年1月27日 · PDIP46 associates with Pol δ in cell extracts both by immunochemical and protein separation methods, as well as by ChIP analyses. PDIP46 also interacts with PCNA via multiple copies of a novel PCNA binding motif, the APIMs …
CDD Conserved Protein Domain Family: RRM_SKAR - National …
This subgroup corresponds to the RRM of SKAR, also termed polymerase delta-interacting protein 3 (PDIP3), 46 kDa DNA polymerase delta interaction protein (PDIP46), belonging to the Aly/REF family of RNA binding proteins that have been implicated in coupling transcription with pre-mRNA splicing and nucleo-cytoplasmic mRNA transport.
PDIP46 (DNA polymerase δ interacting protein 46) is an ... - PubMed
2016年2月2日 · PDIP46 (SKAR, POLDIP3) was discovered through its interaction with the p50 subunit of human DNA polymerase δ (Pol δ). Its functions in DNA replication are unknown. PDIP46 associates with Pol δ in cell extracts both by immunochemical and protein separation methods, as well as by ChIP analyses.
An alternative POLDIP3 transcript promotes ... - ScienceDirect
2017年5月1日 · POLDIP3 is a target of ribosomal protein S6 kinase 1, and regulates DNA replication and mRNA translation. In this study, we measured the expression of an alternative POLDIP3 transcript (POLDIP3-β), which lacks exon 3 and 29 amine acids, in clinical hepatocellular carcinoma (HCC) tissues.
Thirty Years with ERH: An mRNA Splicing and Mitosis Factor Only …
2023年10月13日 · PDIP46/SKAR, DNA polymerase δ and MCM2, a helicase subunit that is present at the origin of replication, were found on chromatin in close proximity to one another . PDIP46/SKAR facilitated DNA synthesis by DNA polymerase δ on complex templates and could interact with PCNA, a processivity factor for DNA polymerases δ and ε .
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