Presynaptic Modulation - an overview | ScienceDirect Topics
Presynaptic modulation refers to the adjustment of the presynaptic input-output relationship in the nervous system through factors like repetitive stimulation and activation of presynaptic …
Local modulation by presynaptic receptors controls neuronal ...
2022年2月28日 · Presynaptic LGIC and GPCR activation by locally released neurotransmitters influences neuronal communication in ways that modify effects of somatic action potentials. …
Local modulation by presynaptic receptors controls neuronal ...
Local GPCR inhibition of DA release is one of the best characterized examples of presynaptic modulation. A variety of neurotransmitters, auto- and heteroreceptors participate in this …
Presynaptic NMDA Receptors - Biology of the NMDA Receptor - NCBI Bookshelf
The resulting allosteric modulation of presynaptic NMDARs produces a significant enhancement in mEPSC frequency during early hippocampal development (P3–4), probably due to an …
Presynaptic signal transduction pathways that modulate synaptic ...
2009年6月1日 · Presynaptic modulation is a crucial factor in the adaptive capacity of the nervous system. The coupling between incoming action potentials and neurotransmitter secretion is …
A Presynaptic Perspective on Transport and Assembly …
We review here our current understanding of the mechanisms that govern the biogenesis, transport, and assembly of the key components for presynaptic neurotransmission, discuss …
Presynaptic calcium channels: specialized control of synaptic ...
2020年3月11日 · Advances in optical and electron microscopic imaging, structural biology and molecular techniques have facilitated recent breakthroughs in our understanding of the …
Energy matters: presynaptic metabolism and the maintenance …
2020年10月5日 · Li and Sheng describe the mechanisms that regulate presynaptic energy supply to ensure that neurons can meet these demands and maintain their functions during periods of …
Layer selective presynaptic modulation of excitatory inputs to ...
2008年1月2日 · We first examined a presynaptic or postsynaptic mechanism of action for the effect of MOR activation on GABA receptor function in all layers of hippocampal CA1 through …
Distinct mechanisms of CB1 and GABAB receptor presynaptic modulation …
2023年1月1日 · Presynaptic modulation by CB1 and GABA B receptors decrease the synaptic efficacy of iSPN‐GPe projections by inhibiting GABA release and ultimately contributes to …