Metastatic SW620 colon cancer cells are primed for death when …
2013年9月12日 · Using a couple of isogenic human colon cancer cell lines derived either from the primary tumor (SW480) or from a lymph node metastasis (SW620), we found that only SW480 cells were sensitive...
SW620 [SW-620] - CCL-227 - ATCC
SW620 [SW-620] cells are isolated from the large intestine of a 51-year-old male Dukes C colorectal cancer patient. The cells can be used for cancer and toxicology research.
Human SW620 cells were isolated from a patient with a colorectal adeno-carcinoma, from a lymph node as metastatic site. A Hematoxylen-Eosin stained paraffin section of a subcutaneous SW620 xenograft is shown in Fig.1. As routine quality controls, the cells are regularly checked for Mycoplasma contamination and authenticity (via STR DNA Typing).
SOX2 promotes chemoresistance, cancer stem cells properties, …
2021年5月5日 · Sex-determining region Y-box2 (SOX2), a master regulator of embryonic and induced pluripotent stem cells, drives cancer stem cells (CSCs) properties, fuels tumor initiation, and contributes to...
Rock inhibition promotes NaV1.5 sodium channel-dependent SW620 …
2020年8月7日 · In this study we used the selective ROCK inhibitor, Y-27632, to address the participation of the Rho-ROCK signalling pathway in the invasive properties of SW620 human colon cancer cells.
In vitro analysis of putative cancer stem cell populations and ...
2018年4月4日 · In the present study, the SW480 and SW620 paired cell lines derived from a colon adenocarcinoma and its lymph node metastasis, respectively were compared as an in vitro model of cancer progression. Their chemosensitivity and CSC properties were investigated.
Characterization of colon cancer cells: a functional approach ...
2012年3月20日 · In vivo growth behaviour studies of SW620 revealed significantly higher take rates and shorter doubling times in the tumour growth of CD133 positive subclones in comparison to the unsorted cell line or CD133 negative subclones.
In vitro and in vivo sensitization of SW620 metastatic colon cancer ...
2009年4月15日 · Given the chemosensitizing properties of the DETANONOate and CDDP combination treatment in vitro, we elected to validate these effects in nude mice bearing SW620 tumor xenografts. Immunocompromised mice were subjected to subcutaneous inoculation with SW620 cells as described in the methods.
SW620 Cell Line - an overview | ScienceDirect Topics
To monitor intracellular caspase-3 activity, we visualized the response of nanoparticle assemblies of human colon carcinoma (SW620) cells upon stimulation of the extrinsic pathway with tumor necrosis factor-α (TNF-α) and cycloheximide (CHX).
Intravasation of SW620 colon cancer cell spheroids through the …
2018年1月1日 · Since mechanisms, of how colon cancer emboli breach the blood microvasculature are poorly defined, we studied a model consisting of SW620 cell spheroids and BECs and report on the correlation between tumour intravasation, 12(S)-HETE levels secreted by SW620 cells, and the NF-κB-dependent response in BECs.
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