Stem-cell niche - Wikipedia
Stem-cell niche refers to a microenvironment, within the specific anatomic location where stem cells are found, which interacts with stem cells to regulate cell fate. [1] The word 'niche' can be in reference to the in vivo or in vitro stem-cell microenvironment.
The Stem Cell Niche: Interactions between Stem Cells and Their ...
Embryonic and adult stem cell research has shown that stem cell fates are controlled by their specialized microenvironment, referred to as the stem cell niche, via direct cell-cell interactions and the molecular signals emitting from the niche.
Stem Cell Niche - an overview | ScienceDirect Topics
Stem cells can be found within the body in a tissue-specific microenvironment called the stem cell niche. The stem cell niche provides cells with both biochemical and physical support to directly influence cellular behavior (Fig. 2). The majority of biochemical cues are the secreted growth factors and cytokines from non-stem cells adjacent or ...
Stem-cell niche - Latest research and news | Nature
2024年12月4日 · A stem-cell niche is an area of a tissue that provides a specific microenvironment, in which stem cells are present in an undifferentiated and self-renewable state.
No place like home: anatomy and function of the stem cell niche
An improved understanding of the relationship between stem cells and their niches will facilitate the recreation of niches in vitro, as well as in vivo manipulation of the niche to...
The emergence of the stem cell niche - PMC - PubMed Central …
A common theme for many niche systems is supporting waves of developing progenitors and stem cells. One of the best understood emerging niche systems is the hematopoietic stem cell (HSC) niche, which supports two HSC waves that give rise to all blood cells.
Tissue Stem Cells: Architects of Their Niches - PMC
Heterologous stem cell niche components include the basement membrane, rich in extracellular matrix and stem cell growth factors, as well as blood vessels, lymphatic capillaries, nerves, stromal, adipose, and a variety of tissue-resident immune cells that function with stem cells to guard against tissue damage and pathogens.
Stem Cell Niche - an overview | ScienceDirect Topics
A stem-cell niche is an anatomic tissue section that offers an intricate and adaptable specialized milieu where stem cells can exist in an undifferentiated, self-renewing form.
The emergence of the stem cell niche: Trends in Cell Biology - Cell …
2022年8月4日 · Emerging niches mature through distinct stages to form the adult niche and enable proper stem cell support. As a model of emerging niches, this review highlights how differences in the skeletal muscle microenvironment influence emerging versus satellite cell (SC) niche formation in skeletal muscle, which is among the most regenerative tissue ...
Tissue Stem Cells: Architects of Their Niches - Cell Press
2020年10月1日 · Heterologous stem cell niche components include the basement membrane, rich in extracellular matrix and stem cell growth factors, as well as blood vessels, lymphatic capillaries, nerves, stromal, adipose, and a variety of tissue-resident immune cells that function with stem cells to guard against tissue damage and pathogens.