Mesangial cell - Wikipedia
Mesangial cells are specialised cells in the kidney that make up the mesangium of the glomerulus. Together with the mesangial matrix, they form the vascular pole of the renal corpuscle. [1] . The mesangial cell population accounts for approximately 30-40% of …
The Mesangial cell — the glomerular stromal cell - Nature
2021年9月10日 · Insights into the molecular phenotype of kidney mesangial cells suggest that they are a specialized stromal cell of the glomerulus. Here, we review our current understanding of mesenchymal stromal...
The Mesangial cell - the glomerular stromal cell - PubMed
Insights into the molecular phenotype of kidney mesangial cells suggest that they are a specialized stromal cell of the glomerulus. Here, we review our current understanding of mesenchymal stromal cells and discuss how it informs the …
Frontiers | The Glomerulus According to the Mesangium
The glomerulus is the functional unit for filtration of blood and formation of primary urine. This intricate structure is composed of the endothelium with its glycocalyx facing the blood, the glomerular basement membrane and the podocytes facing the …
Mesangium - an overview | ScienceDirect Topics
Mesangial cells are irregularly shaped cells which extend processes from their cell body towards the glomerular basement membrane (GBM). The “mesangium” refers to the mesangial cells together with the mesangial matrix they produce71,141 (Figures 22.11 and 22.12).
Mesangial cell biology - ScienceDirect
2012年5月15日 · Mesangial cells (MCs) comprise approximately one third of decapsulated glomerular cell population with endothelial cells and glomerular visceral epithelial cells comprising the rest. MCs maintain the structural architecture of the glomerular capillary similar to the function of certain microvascular pericytes.
The role of the mesangium in glomerular function
2023年9月1日 · When discussing glomerular function, one cell type is often left out, the mesangial cell (MC), probably since it is not a part of the filtration barrier per se. The MCs are instead found between the glomerular capillaries, embedded in their mesangial matrix.
Pathological patterns of mesangioproliferative glomerulonephritis …
Mesangioproliferative glomerulonephritis is an important cause of nephrotic syndrome in young adults in the western region of Saudi Arabia. Future studies from the region are needed to elucidate the clinical relevance of mesangial cell proliferation to the end stage kidney diseases.
Cell biology of mesangial cells: the third cell that maintains the ...
2016年2月24日 · Mesangial cells are situated between glomerular capillary loops and are completely embedded in the mesangial matrix. They form a supporting framework that maintains the structural integrity of the glomerular tuft, including its capillaries.
Mesangial cells: renal function protagonists or coadjuvants?
Strategically located, mesangial cells are directly involved in biological phenomena governing renal physiology and embryology. In this triply integrated circuit, changes occurring in one cell type can produce corresponding effects in others.